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NDB ID: 6QIB    PDB ID: 6QIB     NAKB(beta): 6QIB 


Title:

THE CRYSTAL STRUCTURE OF POL2CORE IN COMPLEX WITH DNA AND AN INCOMING NUCLEOTIDE, CARRYING AN FE-S CLUSTER

Molecular Description:

DNA polymerase epsilon catalytic subunit A/DNA Complex

Deposited:

2019-01-18

Released:

2019-04-17

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ter Beek, J., Parkash, V., Bylund, G.O., Osterman, P., Sauer-Eriksson, A.E., Johansson, E.
Structural evidence for an essential Fe-S cluster in the catalytic core domain of DNA polymerase ε. 
Nucleic Acids Res., 47, pp. 5712 - 5722, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 158.36   b = 70.402   c = 154.24 (Ångstroms)

α = 90.0   β = 112.99   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2265 for 36257 reflections in the resolution range 78.48 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)