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NDB ID: 6QIS    PDB ID: 6QIS 


Title:

CRYSTAL STRUCTURE OF CAG REPEATS WITH SYNTHETIC CMBL3A COMPOUND (MODEL II)

Molecular Description:

RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3')

Deposited:

2019-01-21

Released:

2019-09-25

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Mukherjee, S., Blaszczyk, L., Rypniewski, W., Falschlunger, C., Micura, R., Murata, A., Dohno, C., Nakatani, K., Kiliszek, A.
Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. 
Nucleic Acids Res., 47, pp. 10906 - 10913, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 45.81   b = 51.154   c = 118.463 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2412 for 19465 reflections in the resolution range 42.73 to 1.99 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)