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NDB ID: 6QIT    PDB ID: 6QIT 


Title:

CRYSTAL STRUCTURE OF CAG REPEATS WITH SYNTHETIC CMBL3B COMPOUND

Molecular Description:

RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3')

Deposited:

2019-01-21

Released:

2019-09-25

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Mukherjee, S., Blaszczyk, L., Rypniewski, W., Falschlunger, C., Micura, R., Murata, A., Dohno, C., Nakatani, K., Kiliszek, A.
Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. 
Nucleic Acids Res., , pp. - , 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 35.233   b = 50.989   c = 39.554 (Ångstroms)

α = 90.0   β = 104.06   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1527 for 20920 reflections in the resolution range 29.3 to 1.501 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)