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NDB ID: 6S0M    PDB ID: 6S0M 


Title:

STRUCTURAL AND DYNAMIC STUDIES PROVIDE INSIGHTS INTO SPECIFICITY AND ALLOSTERIC REGULATION OF RIBONUCLEASE AS, A KEY ENZYME IN MYCOBACTERIAL VIRULENCE

Molecular Description:

3'-5' exoribonuclease/RNA Complex

Deposited:

2019-06-17

Released:

2019-08-28

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Calvanese, L., Squeglia, F., Romano, M., D'Auria, G., Falcigno, L., Berisio, R.
Structural and dynamic studies provide insights into specificity and allosteric regulation of ribonuclease as, a key enzyme in mycobacterial virulence. 
J.Biomol.Struct.Dyn., , pp. 1 - 13, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 42.464   b = 77.068   c = 104.572 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.18104 for 21440 reflections in the resolution range 30.0 to 2.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)