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NDB ID: 6SCE    PDB ID: 6SCE 


Title:

STRUCTURE OF A TYPE III CRISPR DEFENCE DNA NUCLEASE ACTIVATED BY CYCLIC OLIGOADENYLATE

Molecular Description:

Uncharacterized protein/DNA Complex

Deposited:

2019-07-24

Released:

2020-02-19

Structural Keywords:

SMALL NA FRAGMENT, CYCLIC

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

McMahon, S.A., Zhu, W., Graham, S., Rambo, R., White, M.F., Gloster, T.M.
Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate. 
Nat Commun, 11, pp. 500 - 500, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 84.37   b = 84.52   c = 123.1 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.17813 for 74943 reflections in the resolution range 59.7 to 1.83 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)