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NDB ID: 6TQA    PDB ID: 6TQA 


Title:

X-RAY STRUCTURE OF ROQUIN ROQ DOMAIN IN COMPLEX WITH A UCP3 CDE2 SL RNA MOTIF

Molecular Description:

Roquin-1/RNA Complex

Deposited:

2019-12-16

Released:

2020-05-27

Structural Keywords:

A DOUBLE HELIX, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Binas, O., Tants, J.N., Peter, S.A., Janowski, R., Davydova, E., Braun, J., Niessing, D., Schwalbe, H., Weigand, J.E., Schlundt, A.
Structural basis for the recognition of transiently structured AU-rich elements by Roquin. 
Nucleic Acids Res., , pp. - , 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 44.53   b = 160.66   c = 68.01 (Ångstroms)

α = 90.0   β = 107.96   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2001 for 33655 reflections in the resolution range 42.4 to 2.4 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)