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NDB ID: 6TQI    PDB ID: 6TQI 


Title:

I-MOTIF STRUCTURE FORMED FROM THE C STRAND OF A HUMAN TELOMERE FRAGMENT

Molecular Description:

DNA (5'-*TP*AP*AP*CP*CP*CP*TP*AP*A-3')

Deposited:

2019-12-16

Released:

2020-06-10

Structural Keywords:

QUADRUPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Zhang, Y., El Omari, K., Duman, R., Liu, S., Haider, S., Wagner, A., Parkinson, G.N., Wei, D.
Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths. 
Nucleic Acids Res., , pp. - , 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 62 2 2

Cell Constants:

a = 31.9   b = 31.9   c = 81.88 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2384 for 647 reflections in the resolution range 25.0 to 2.95 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)