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NDB ID: 6U6Z    PDB ID: 6U6Z 


Title:

HUMAN SAMHD1 BOUND TO DEOXYRIBO(TG*TTCA)-OLIGONUCLEOTIDE

Molecular Description:

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1/DNA Complex

Deposited:

2019-08-30

Released:

2020-09-02

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yu, C.H., Bhattacharya, A., Wang, Z., Taylor, A.B., Persaud, M., Bulnes-Ramos, A., Xu, J., Selyutina, A., Martinez-Lopez, A., Demeler, B., Kim, B., Diaz-Griffero, F., Ivanov, D.N.
The GpsN modification enhances affinity of nucleic acid binding by SAMHD1
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 81.61   b = 94.67   c = 96.32 (Ångstroms)

α = 72.9   β = 70.95   γ = 64.96 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1752 for 131789 reflections in the resolution range 68.27 to 2.1 Ångstroms with Fobs >  1.96 sigma(Fobs) and with I >  0.0 sigma(I)