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NDB ID: 6U7T    PDB ID: 6U7T 


Title:

MUTY ADENINE GLYCOSYLASE BOUND TO DNA CONTAINING A TRANSITION STATE ANALOG (1N) PAIRED WITH D(8-OXO-G)

Molecular Description:

A/G-specific adenine glycosylase/DNA Complex

Deposited:

2019-09-03

Released:

2019-10-02

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Russelburg, L.P., O'Shea Murray, V.L., Demir, M., Knutsen, K.R., Sehgal, S.L., Cao, S., David, S.S., Horvath, M.P.
Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY. 
Acs Chem.Biol., 15, pp. 93 - 102, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 37.8   b = 86.49   c = 140.58 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2618 for 30194 reflections in the resolution range 41.334 to 2.0 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)