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NDB ID: 6UEJ    PDB ID: 6UEJ 


Title:

CRYSTAL STRUCTURE OF HUMAN ZINC FINGER ANTIVIRAL PROTEIN BOUND TO RNA

Molecular Description:

Zinc finger CCCH-type antiviral protein 1/RNA Complex

Deposited:

2019-09-21

Released:

2019-11-13

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Meagher, J.L., Takata, M., Goncalves-Carneiro, D., Keane, S.C., Rebendenne, A., Ong, H., Orr, V.K., MacDonald, M.R., Stuckey, J.A., Bieniasz, P.D., Smith, J.L.
Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences. 
Proc.Natl.Acad.Sci.USA, , pp. - , 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65

Cell Constants:

a = 123.09   b = 123.09   c = 40.67 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the BUSTER program. The R value is 0.213 for 18076 reflections in the resolution range 38.0 to 2.21 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)