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NDB ID: 6UEU    PDB ID: 6UEU 


Title:

CRYSTAL STRUCTURE OF BF DNA POLYMERASE F710Y MUTANT BOUND TO TETRAHYDROFURAN AND DATP

Molecular Description:

DNA polymerase I/DNA Complex

Deposited:

2019-09-23

Released:

2020-09-30

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Walsh, A.R., Beese, L.S., Wu, E.Y.
Structural basis for blockage of DNA synthesis by a thymine dimer lesion in a high-fidelity DNA polymerase
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 93.875   b = 109.068   c = 150.096 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2024 for 138444 reflections in the resolution range 44.987 to 1.8 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)