A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 8-Jul-2020 number of released structures: 10846
Search for released structures

NDB ID: 6VYP    PDB ID: 6VYP 


Title:

CRYSTAL STRUCTURE OF THE LSD1/COREST HISTONE DEMETHYLASE BOUND TO ITS NUCLEOSOME SUBSTRATE

Molecular Description:

Histone H3
Histone H4
Histone H2A type 1
Histone H2B 1.1
Lysine-specific histone demethylase 1A
REST corepressor 1/DNA Complex

Deposited:

2020-02-27

Released:

2020-05-27

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 6 protein sequences

Primary Citation:

Kim, S.A., Zhu, J., Yennawar, N., Eek, P., Tan, S.
Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate. 
Mol.Cell, 78, pp. 903 - , 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 103.771   b = 335.77   c = 174.633 (Ångstroms)

α = 90.0   β = 91.07   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2309 for 50660 reflections in the resolution range 20.17 to 4.99 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)