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NDB ID: 6W0Q    PDB ID: 6W0Q 


Title:

APE1 ENDONUCLEASE PRODUCT COMPLEX D148E

Molecular Description:

DNA-(apurinic or apyrimidinic site) lyase/DNA Complex

Deposited:

2020-03-02

Released:

2020-06-10

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Whitaker, A.M., Stark, W.J., Flynn, T.S., Freudenthal, B.D.
Molecular and structural characterization of disease-associated APE1 polymorphisms. 
DNA Repair (Amst.), 91-92, pp. 102867 - 102867, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 44.435   b = 60.496   c = 72.982 (Ångstroms)

α = 83.512   β = 79.622   γ = 88.615 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1872 for 111259 reflections in the resolution range 24.81 to 1.89 Ångstroms with Fobs >  1.96 sigma(Fobs) and with I >  0.0 sigma(I)