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NDB ID: 6W0R    PDB ID: 6W0R 


Title:

HUMAN 8-OXOGUANINE GLYCOSYLASE INTERROGATING FULLY INTRAHELICAL UNDAMAGED DNA

Molecular Description:

N-glycosylase/DNA lyase/DNA Complex

Deposited:

2020-03-02

Released:

2020-09-23

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Shigdel, U.K., Ovchinnikov, V., Lee, S.J., Shih, J.A., Karplus, M., Nam, K., Verdine, G.L.
The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. 
Nat Commun, 11, pp. 4437 - 4437, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 88.928   b = 88.928   c = 210.539 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2104 for 21448 reflections in the resolution range 43.5 to 2.35 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)