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NDB ID: 6W4T    PDB ID: 6W4T 


Title:

APE1 Y269A PHOSPHOROTHIOATE SUBSTRATE COMPLEX WITH ABASIC DNA

Molecular Description:

DNA-(apurinic or apyrimidinic site) lyase/DNA Complex

Deposited:

2020-03-11

Released:

2020-06-17

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hoitsma, N.M., Whitaker, A.M., Beckwitt, E.C., Jang, S., Agarwal, P.K., Van Houten, B., Freudenthal, B.D.
Characterizing the APE1 DNA Intercalating Loop During DNA Sculpting
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 45.659   b = 148.315   c = 153.235 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.224 for 27026 reflections in the resolution range 48.29 to 2.77 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)