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NDB ID: 6W7A    PDB ID: 6W7A 


Title:

THE CRYSTAL STRUCTURE OF THE 2009/H1N1/CALIFORNIA PA ENDONUCLEASE MUTANT E119D BOUND TO DNA OLIGOMER TAGCAT (UNCLEAVED, 5MM OVERNIGHT DNA SOAK)

Molecular Description:

Polymerase acidic protein

Deposited:

2020-03-18

Released:

2021-02-03

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Kumar, G., Cuypers, M., Webby, R.R., Webb, T.R., White, S.W.
Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism. 
Nucleic Acids Res., 49, pp. 1609 - 1618, 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 4 2 2

Cell Constants:

a = 89.301   b = 89.301   c = 134.024 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.176 for 16274 reflections in the resolution range 39.95 to 2.09 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)