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NDB ID: 6W8W    PDB ID: 6W8W 


Title:

CRYSTAL STRUCTURE OF MOUSE DNMT1 IN COMPLEX WITH CCG DNA

Molecular Description:

DNA (cytosine-5)-methyltransferase 1/DNA Complex

Deposited:

2020-03-21

Released:

2020-07-08

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Adam, S., Anteneh, H., Hornisch, M., Wagner, V., Lu, J., Radde, N.E., Bashtrykov, P., Song, J., Jeltsch, A.
DNMT1 activity, base flipping mechanism and genome-wide DNA methylation are regulated by the DNA sequence context
Nat Commun, , pp. - , 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 89.794   b = 152.593   c = 95.631 (Ångstroms)

α = 90.0   β = 94.74   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2398 for 50812 reflections in the resolution range 48.44 to 3.0 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)