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NDB ID: 6WEA    PDB ID: 6WEA 


Title:

YTH DOMAIN OF HUMAN YTHDC1 WITH A 10MER OLIGO CONTAINING N6MA

Molecular Description:

YTH domain-containing protein 1/DNA Complex

Deposited:

2020-04-01

Released:

2020-07-15

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Woodcock, C.B., Horton, J.R., Zhou, J., Bedford, M.T., Blumenthal, R.M., Zhang, X., Cheng, X.
Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA. 
Nucleic Acids Res., , pp. - , 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 82.936   b = 42.641   c = 119.869 (Ångstroms)

α = 90.0   β = 101.791   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2112 for 73624 reflections in the resolution range 40.59 to 1.8 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)