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NDB ID: 6WID    PDB ID: 6WID 


Title:

NUCLEOTIDE INCORPORATION INTERMEDIATE INTO QUATERNARY COMPLEX OF HUMAN POLYMERASE MU ON A COMPLEMENTARY DNA DOUBLE-STRAND BREAK SUBSTRATE

Molecular Description:

DNA-directed DNA/RNA polymerase mu/DNA Complex

Deposited:

2020-04-09

Released:

2020-10-07

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 4 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Kaminski, A.M., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Pedersen, L.C., Bebenek, K.
Structural snapshots of human DNA polymerase mu engaged on a DNA double-strand break. 
Nat Commun, 11, pp. 4784 - 4784, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 60.186   b = 62.04   c = 118.32 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1644 for 71176 reflections in the resolution range 31.02 to 1.5 Ångstroms with Fobs >  1.37 sigma(Fobs) and with I >  0.0 sigma(I)