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NDB ID: 6WMC    PDB ID: 6WMC 


Title:

CRYSTAL STRUCTURE OF A SOLUBLE VARIANT OF FULL-LENGTH HUMAN APOBEC3G (PH 9.0)

Molecular Description:

APOLIPOPROTEIN B MRNA EDITING ENZYME
CATALYTIC PEPTIDE-3 LIKE 3G/DNA Complex

Deposited:

2020-04-21

Released:

2020-12-23

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Maiti, A., Myint, W., Delviks-Frankenberry, K.A., Hou, S., Kanai, T., Balachandran, V., Sierra Rodriguez, C., Tripathi, R., Kurt Yilmaz, N., Pathak, V.K., Schiffer, C.A., Matsuo, H.
Crystal Structure of a Soluble APOBEC3G Variant Suggests ssDNA to Bind in a Channel that Extends between the Two Domains. 
J.Mol.Biol., 432, pp. 6042 - 6060, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 1 2 1

Cell Constants:

a = 60.233   b = 42.091   c = 191.911 (Ångstroms)

α = 90.0   β = 95.939   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2222 for 5588 reflections in the resolution range 47.72 to 3.49 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)