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NDB ID: 6WRE    PDB ID: 6WRE 


Title:

CRYSTAL STRUCTURE OF MOUSE DXO IN COMPLEX WITH 5'-OH RNA SUBSTRATE MIMIC AND CALCIUM ION

Molecular Description:

Decapping and exoribonuclease protein/RNA Complex

Deposited:

2020-04-29

Released:

2020-05-13

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Doamekpor, S.K., Gozdek, A., Kwasnik, A., Kufel, J., Tong, L.
A novel 5'-hydroxyl dinucleotide hydrolase activity for the DXO/Rai1 family of enzymes. 
Nucleic Acids Res., 48, pp. 349 - 358, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 50.182   b = 87.795   c = 53.88 (Ångstroms)

α = 90.0   β = 112.35   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1896 for 29060 reflections in the resolution range 49.83 to 2.0 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)