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NDB ID: 6WXY    PDB ID: 6WXY 


Title:

CRYSTAL STRUCTURE OF CA6-BOUND CARD1

Molecular Description:

Card1/RNA Complex

Deposited:

2020-05-12

Released:

2020-12-30

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Rostol, J.T., Xie, W., Kuryavyi, V., Maguin, P., Kao, K., Froom, R., Patel, D.J., Marraffini, L.A.
The Card1 nuclease provides defence during type III CRISPR immunity. 
Nature, 590, pp. 624 - 629, 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 172.911   b = 124.763   c = 42.259 (Ångstroms)

α = 90.0   β = 96.79   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2081 for 50768 reflections in the resolution range 85.85 to 2.1 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)