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NDB ID: 6X5N    PDB ID: 6X5N 


Title:

CRYSTAL STRUCTURE OF A STABILIZED PAN ENE BIMOLECULAR TRIPLEX WITH A GC-CLAMPED POLYA TAIL

Molecular Description:

Light chain Fab BL-3 6
Heavy chain Fab Bl-3 6/RNA Complex

Deposited:

2020-05-26

Released:

2020-07-01

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Swain, M., Li, M., Ageeli, A., Kasprzak, W., Miller, J.T., Sztuba-Solinska, J., Kenderdine, T., Fraboni, A., Schneekloth, J., Piccirrili, J., Murelli, R.P., Fabris, D., Wlodawer, A., Shapiro, B., Baird, N., Le Grice, S.F.J.
Targeting the Nuclear Expression Element (ENE) Triple Helix of Kaposi Sarcoma Herpesvirus Polyadenylated Nuclear RNA, PAN.
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 43.299   b = 76.182   c = 110.523 (Ångstroms)

α = 72.223   β = 88.584   γ = 86.569 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1831 for 18300 reflections in the resolution range 37.99 to 3.3 Ångstroms with Fobs >  2.18 sigma(Fobs) and with I >  0.0 sigma(I)