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NDB ID: 6XB7    PDB ID: 6XB7 


Title:

IRES-TARGETING SMALL MOLECULE INHIBITS ENTEROVIRUS 71 REPLICATION VIA ALLOSTERIC STABILIZATION OF A TERNARY COMPLEX

Molecular Description:

RNA (41-MER)

Deposited:

2020-06-05

Released:

2020-09-02

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Davila Calderon, J., Tolbert, B.S.
Small Molecule Targeting IRES Domain Inhibits Enterovirus 71 Replication via an Allosteric Mechanism that Stabilizes a Ternary Complex
To Be Published, , pp. - , 0.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 10 Structures

Sample Details:

200 uM Selective Deuteration; Fully Deuteration for U and C; Selective Deuteration for A and G rNTP, 800 uM DMA135, 100% D2O 100% D2O