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NDB ID: 6XCL    PDB ID: 6XCL 


Title:

CRYSTAL STRUCTURE OF HUMAN TELOMERIC DNA G-QUADRUPLEX IN COMPLEX WITH A NOVEL PLATINUM(II) COMPLEX.

Molecular Description:

DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3')

Deposited:

2020-06-08

Released:

2020-11-04

Structural Keywords:

QUADRUPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Miron, C.E., van Staalduinen, L., Rangaswamy, A.M.M., Chen, M., Liang, Y., Jia, Z., Mergny, J.L., Petitjean, A.
Going Platinum to the Tune of a Remarkable Guanine Quadruplex Binder: Solution- and Solid-State Investigations. 
Angew.Chem.Int.Ed.Engl., , pp. - , 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 3

Cell Constants:

a = 64.03   b = 64.03   c = 42.23 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1938 for 10574 reflections in the resolution range 33.6 to 2.7 Ångstroms with Fobs >  1.39 sigma(Fobs) and with I >  0.0 sigma(I)