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NDB ID: 6XL1    PDB ID: 6XL1 


Title:

CRYSTAL STRUCTURE OF CA4-ACTIVATED CARD1(D294N)

Molecular Description:

Card1/RNA Complex

Deposited:

2020-06-27

Released:

2020-12-30

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Rostol, J.T., Xie, W., Kuryavyi, V., Maguin, P., Kao, K., Froom, R., Patel, D.J., Marraffini, L.A.
The Card1 nuclease provides defence during type III CRISPR immunity. 
Nature, 590, pp. 624 - 629, 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 111.946   b = 111.946   c = 172.18 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1791 for 80121 reflections in the resolution range 39.58 to 1.95 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)