A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 23-Sep-2020 number of released structures: 10967
Search for released structures

NDB ID: 6XQE    PDB ID: 6XQE 


Title:

CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH SARECYCLINE, UAA-MRNA, AND DEACYLATED P-SITE TRNA AT 3.00A RESOLUTION

Molecular Description:

Deposited:

2020-07-09

Released:

2020-08-05

Nucleic Acid Sequence:

Click to show/hide 5 nucleic acid sequences

Protein Sequence:

Click to show/hide 49 protein sequences

Primary Citation:

Batool, Z., Lomakin, I.B., Polikanov, Y.S., Bunick, C.G.
Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. 
Proc.Natl.Acad.Sci.USA, 117, pp. 20530 - 20537, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 209.13   b = 448.15   c = 621.94 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2494 for 1140041 reflections in the resolution range 86.77 to 3.0 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)