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NDB ID: 6XWG    PDB ID: 6XWG 


Title:

CRYSTAL STRUCTURE OF THE HUMAN RXR/RAR DNA-BINDING DOMAIN HETERODIMER BOUND TO THE HUMAN RARB2 DR5 RESPONSE ELEMENT

Molecular Description:

Retinoic acid receptor RXR-alpha
Retinoic acid receptor alpha/DNA Complex

Deposited:

2020-01-23

Released:

2020-09-09

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Osz, J., McEwen, A.G., Bourguet, M., Przybilla, F., Peluso-Iltis, C., Poussin-Courmontagne, P., Mely, Y., Cianferani, S., Jeffries, C.M., Svergun, D.I., Rochel, N.
Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR
Nucleic Acids Res., , pp. - , 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43 21 2

Cell Constants:

a = 56.714   b = 56.714   c = 238.364 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the BUSTER program. The R value is 0.192 for 12203 reflections in the resolution range 26.51 to 2.4 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)