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NDB ID: 6Y39    PDB ID: 6Y39 


Title:

HAPE-P88L MUTANT CCAAT-BINDING COMPLEX FROM ASPERGILLUS NIDULANS WITH CYCA DNA

Molecular Description:

HapB
Transcription factor HapC (Eurofung)
CBFD_NFYB_HMF domain-containing protein/DNA Complex

Deposited:

2020-02-17

Released:

2020-05-27

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Hortschansky, P., Misslinger, M., Morl, J., Gsaller, F., Bromley, M.J., Brakhage, A.A., Groll, M., Haas, H., Huber, E.M.
Structural basis of HapEP88L-linked antifungal triazole resistance inAspergillus fumigatus. 
Life Sci Alliance, 3, pp. - , 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 72.15   b = 103.5   c = 159.71 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2225 for 50185 reflections in the resolution range 30.0 to 2.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)