A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 18-Nov-2020 number of released structures: 11059
Search for released structures

NDB ID: 6Z1A    PDB ID: 6Z1A 


Title:

TERNARY COMPLEX OF STAPHYLOCOCCUS AUREUS DNA GYRASE WITH AMK12 AND DNA

Molecular Description:

DNA gyrase subunit B
DNA gyrase subunit A/DNA Complex

Deposited:

2020-05-13

Released:

2020-11-11

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Kolaric, A., Germe, T., Hrast, M., Stevenson, C.E.M., Lawson, D.M., Burton, N., Voros, J., Maxwell, A., Minovski, N., Anderluh, M.
Potent novel DNA gyrase inhibitors bind asymmetrically to their target using unforeseen symmetrical halogen bonds
To be published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 92.592   b = 92.592   c = 405.464 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.181 for 82229 reflections in the resolution range 80.32 to 2.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)