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NDB ID: 7ABS    PDB ID: 7ABS 


Title:

STRUCTURE OF HUMAN DCLRE1C/ARTEMIS IN COMPLEX WITH DNA - RE-EVALUATION OF 6WO0

Molecular Description:

Deposited:

2020-09-08

Released:

2021-08-04

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yosaatmadja, Y., Baddock, H.T., Newman, J.A., Bielinski, M., Gavard, A.E., Mukhopadhyay, S.M.M., Dannerfjord, A.A., Schofield, C.J., McHugh, P.J., Gileadi, O.
Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition. 
Nucleic Acids Res., , pp. - , 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 72.69   b = 111.01   c = 55.16 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.21802 for 30565 reflections in the resolution range 34.54 to 1.97 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)