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NDB ID: 7BDV    PDB ID: 7BDV 


Title:

STRUCTURE OF CAN2 FROM SULFOBACILLUS THERMOSULFIDOOXIDANS IN COMPLEX WITH CYCLIC TETRA-ADENYLATE (CA4)

Molecular Description:

Can2/RNA Complex

Deposited:

2020-12-22

Released:

2021-03-03

Structural Keywords:

, CYCLIC

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Zhu, W., McQuarrie, S., Gruschow, S., McMahon, S.A., Graham, S., Gloster, T.M., White, M.F.
The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence. 
Nucleic Acids Res., 49, pp. 2777 - 2789, 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 75.86   b = 85.97   c = 237.91 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2433 for 97728 reflections in the resolution range 51.37 to 2.02 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)