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NDB ID: 7D12    PDB ID: 7D12 


Title:

NMR SOLUTION STRUCTURES OF CAG RNA-DB213 BINDING COMPLEX

Molecular Description:

RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*CP*UP*UP*CP*GP*GP*CP*AP*GP*CP*AP*GP*C)-3')

Deposited:

2020-09-12

Released:

2021-05-12

Structural Keywords:

A DOUBLE HELIX, LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Peng, S., Guo, P., Lin, X., An, Y., Sze, K.H., Lau, M.H.Y., Chen, Z.S., Wang, Q., Li, W., Sun, J.K., Ma, S.Y., Chan, T.F., Lau, K.F., Ngo, J.C.K., Kwan, K.M., Wong, C.H., Lam, S.L., Zimmerman, S.C., Tuccinardi, T., Zuo, Z., Au-Yeung, H.Y., Chow, H.M., Chan, H.Y.E.
CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration. 
Proc.Natl.Acad.Sci.USA, 118, pp. - , 2021.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 5 Structures

Sample Details:

0.4 mM No RNA, 0.4 mM No Ligand, 10.0 mM No NaPi, 0.02 mM No DSS, 0.1 mM No EDTA, 100% D2O 100% D2O