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NDB ID: 7K33    PDB ID: 7K33 


Title:

CRYSTAL STRUCTURE OF ENDONUCLEASE Q COMPLEX WITH 27-MER DUPLEX SUBSTRATE WITH AN ABASIC LESION AT THE ACTIVE SITE

Molecular Description:

Endonuclease Q/DNA complex

Deposited:

2020-09-10

Released:

2021-03-17

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Shi, K., Moeller, N.H., Banerjee, S., McCann, J.L., Carpenter, M.A., Yin, L., Moorthy, R., Orellana, K., Harki, D.A., Harris, R.S., Aihara, H.
Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q. 
Proc.Natl.Acad.Sci.USA, 118, pp. - , 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

H 3

Cell Constants:

a = 151.5   b = 151.5   c = 119.38 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1928 for 12336 reflections in the resolution range 88.3 to 3.11 Ångstroms with Fobs >  1.99 sigma(Fobs) and with I >  0.0 sigma(I)