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NDB ID: 7K96    PDB ID: 7K96 


Title:

HUMAN DNA POLYMERASE BETA TERNARY COMPLEX WITH TEMPLATING CYTOSINE AND INCOMING DEOXYGUANOSINE DIPHOSPHATE

Molecular Description:

DNA polymerase beta/DNA Complex

Deposited:

2020-09-28

Released:

2021-02-03

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Varela, F.A., Freudenthal, B.D.
Mechanism of Deoxyguanosine Diphosphate Insertion by Human DNA Polymerase beta. 
Biochemistry, 60, pp. 373 - 380, 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 50.8   b = 80.4   c = 55.5 (Ångstroms)

α = 90.0   β = 107.9   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1892 for 23635 reflections in the resolution range 25.0 to 2.1 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)