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NDB ID: 7KED    PDB ID: 7KED 


Title:

RNA POLYMERASE II ELONGATION COMPLEX WITH UNNATURAL BASE DTPT3

Molecular Description:

Deposited:

2020-10-10

Released:

2021-06-23

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 10 protein sequences

Primary Citation:

Oh, J., Shin, J., Unarta, I.C., Wang, W., Feldman, A.W., Karadeema, R.J., Xu, L., Xu, J., Chong, J., Krishnamurthy, R., Huang, X., Romesberg, F.E., Wang, D.
Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. 
Nat.Chem.Biol., 17, pp. 906 - 914, 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 169.89   b = 223.01   c = 194.7 (Ångstroms)

α = 90.0   β = 101.6   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2668 for 79870 reflections in the resolution range 82.597 to 3.6 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)