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NDB ID: 7KR3    PDB ID: 7KR3 


Title:

HUMAN DNA LIGASE 1(E346A/E592A) BOUND TO A BULGED DNA SUBSTRATE

Molecular Description:

DNA ligase 1/DNA Complex

Deposited:

2020-11-18

Released:

2021-02-03

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Williams, J.S., Tumbale, P.P., Arana, M.E., Rana, J.A., Williams, R.S., Kunkel, T.A.
High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication. 
Nat Commun, 12, pp. 482 - 482, 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 73.681   b = 101.665   c = 115.5 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1974 for 21866 reflections in the resolution range 36.84 to 2.778 Ångstroms with Fobs >  1.39 sigma(Fobs) and with I >  0.0 sigma(I)