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NDB ID: 7KTI    PDB ID: 7KTI 


Title:

DNA POLYMERASE MU, 8-OXODGTP:CT PRODUCT STATE TERNARY COMPLEX, 20 UM MN2+ (120MIN)

Molecular Description:

Deposited:

2020-11-24

Released:

2022-05-11

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Jamsen, J.A., Sassa, A., Shock, D.D., Beard, W.A., Wilson, S.H.
Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. 
Nat Commun, 12, pp. 2059 - 2059, 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 59.965   b = 68.716   c = 110.586 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1626 for 64388 reflections in the resolution range 34.986 to 1.57 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)