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NDB ID: 7KUM    PDB ID: 7KUM 


Title:

LNA MODIFICATION AT 3' END OF RNA PRIMER COMPLEX WITH GUANOSINE DINUCLEOTIDE LIGAND G(5')PPP(5')G

Molecular Description:

Deposited:

2020-11-25

Released:

2021-09-08

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Giurgiu, C., Fang, Z., Aitken, H.R.M., Kim, S.C., Pazienza, L., Mittal, S., Szostak, J.W.
Structure-activity relationships in nonenzymatic template-directed RNA synthesis. 
Angew.Chem.Int.Ed.Engl., , pp. - , 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 3 2 1

Cell Constants:

a = 47.769   b = 47.769   c = 84.122 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.0 for 11701 reflections in the resolution range 50.0 to 1.714 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)