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NDB ID: 7L34    PDB ID: 7L34 


Title:

HUMAN DNA LIGASE 1 - R641L NICKED DNA COMPLEX

Molecular Description:

DNA ligase 1/DNA Complex

Deposited:

2020-12-17

Released:

2021-01-13

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Jurkiw, T.J., Tumbale, P.P., Schellenberg, M.J., Cunningham-Rundles, C., Williams, R.S., O'Brien, P.J.
LIG1 syndrome mutations remodel a cooperative network of ligand binding interactions to compromise ligation efficiency
To be published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 61.93   b = 110.745   c = 114.858 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1699 for 62117 reflections in the resolution range 39.36 to 1.901 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)