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NDB ID: 7L6R    PDB ID: 7L6R 


Title:

CRYSTAL STRUCTURE OF SARS-COV-2 NSP16/10 HETERODIMER IN COMPLEX WITH (M7GPPPA2M)PUPUPAPAPA (CAP-1), S-ADENOSYL-L-HOMOCYSTEINE (SAH) AND MANGANESE (MN).

Molecular Description:

2'-O-methyltransferase
Non-structural protein 10
RNA (5'-D(*(M7G))-R(P*(A2M)P*UP*U)-3')

Deposited:

2020-12-23

Released:

2021-01-06

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Minasov, G., Shuvalova, L., Rosas-Lemus, M., Kiryukhina, O., Brunzelle, J.S., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and Manganese (Mn).
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 168.757   b = 168.757   c = 52.272 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.1512 for 56344 reflections in the resolution range 29.95 to 1.98 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)