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NDB ID: 7MXT    PDB ID: 7MXT     NAKB: 7MXT 


Title:

CRYSTAL STRUCTURE OF HUMAN EXONUCLEASE 1 EXO1 (WT) IN COMPLEX WITH 5' RECESSED-END DNA (CMR)

Molecular Description:

Deposited:

2021-05-19

Released:

2023-05-10

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Shi, Y., Hellinga, H.W., Beese, L.S.
Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43 21 2

Cell Constants:

a = 72.857   b = 72.857   c = 181.382 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2151 for 9870 reflections in the resolution range 38.498 to 3.048 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)