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NDB ID: 7MXW    PDB ID: 7MXW     NAKB: 7MXW 


Title:

CRYSTAL STRUCTURE OF HUMAN EXONUCLEASE 1 EXO1 (WT) IN COMPLEX WITH 5' FLAP DNA (UF1)

Molecular Description:

Deposited:

2021-05-19

Released:

2023-05-10

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Shi, Y., Hellinga, H.W., Beese, L.S.
Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43 21 2

Cell Constants:

a = 71.955   b = 71.955   c = 179.874 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.223 for 10331 reflections in the resolution range 30.298 to 2.836 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)