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NDB ID: 7N5S    PDB ID: 7N5S     NAKB: 7N5S 


Title:

ZBTB7A ZINC FINGER DOMAIN BOUND TO -200 SITE OF FETAL GLOBIN PROMOTER (OLIGO 6)

Molecular Description:

Deposited:

2021-06-06

Released:

2021-08-25

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yang, Y., Ren, R., Ly, L.C., Horton, J.R., Li, F., Quinlan, K.G.R., Crossley, M., Shi, Y., Cheng, X.
Structural basis for human ZBTB7A action at the fetal globin promoter. 
Cell Rep, 36, pp. 109759 - 109759, 2021.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 2 1

Cell Constants:

a = 46.938   b = 36.963   c = 74.257 (Ångstroms)

α = 90.0   β = 100.012   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2283 for 10124 reflections in the resolution range 36.32 to 2.86 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)