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NDB ID: 7Q4L    PDB ID: 7Q4L 


Title:

THE SOLUTION STRUCTURE OF HSDND1 RRM12 BOUND TO CUUAUUUG RNA

Molecular Description:

Deposited:

2021-10-31

Released:

2022-05-04

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Duszczyk, M.M., Wischnewski, H., Kazeeva, T., Arora, R., Loughlin, F.E., von Schroetter, C., Pradere, U., Hall, J., Ciaudo, C., Allain, F.H.-T.
The solution structure of Dead End bound to AU-rich RNA reveals an unprecedented mode of tandem RRM-RNA recognition required for mRNA regulation
To Be Published, , pp. - , 0.

Experimental Information:

SOLUTION NMR

Space Group:

P 1

Number of Models:

Number of Models: 20 Structures

Sample Details:

0.8 mM fractionally deuterated, 13C,15N-labeled hsDnd1 RRM12, 0.9 mM RNA (5'-R(*CP*UP*UP*AP*UP*UP*UP*G)-3'), 100 mM KHPO4/ KH2PO4 pH 6.6, 1 mM DTT, 95% H2O/5% D2O 95% H2O/5% D2O