A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 29-Jun-2022 number of released structures: 12153
Search for released structures

NDB ID: 7RH2    PDB ID: 7RH2 


Title:

IRF4 TRANSCRIPTION FACTOR MUTANT -K59R

Molecular Description:

Deposited:

2021-07-16

Released:

2022-05-25

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Sundararaj, S., Seneviratne, S., Williams, S.J., Enders, A., Casarotto, M.G.
The molecular basis for the development of adult T-cell leukemia/lymphoma in patients with an IRF4 K59R mutation. 
Protein Sci., 31, pp. 787 - 796, 2022.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 114.874   b = 114.874   c = 154.788 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2052 for 42580 reflections in the resolution range 46.12 to 2.47 Ångstroms with Fobs >  1.38 sigma(Fobs) and with I >  0.0 sigma(I)