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NDB ID: 7S3C    PDB ID: 7S3C 


Title:

CRYSTAL STRUCTURE OF INTACT U2AF65 RRM-REGION BOUND TO ADML-A5 OLIGONUCLEOTIDE

Molecular Description:

Deposited:

2021-09-05

Released:

2022-05-25

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Glasser, E., Maji, D., Biancon, G., Puthenpeedikakkal, A.M.K., Cavender, C.E., Tebaldi, T., Jenkins, J.L., Mathews, D.H., Halene, S., Kielkopf, C.L.
Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. 
Nucleic Acids Res., 50, pp. 5299 - 5312, 2022.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 43.549   b = 55.771   c = 76.414 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1607 for 54400 reflections in the resolution range 37.84 to 1.51 Ångstroms with Fobs >  1.9 sigma(Fobs) and with I >  0.0 sigma(I)