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NDB ID: 7U75    PDB ID: 7U75 


Title:

HUMAN DNA POLYMERASE ETA-DNA TERNARY MISMATCH COMPLEX:REACTION WITH 0.5 MM MN2+ FOR 1800S THEN WITH 10 MM MN2+ FOR 90S

Molecular Description:

Deposited:

2022-03-07

Released:

2022-05-04

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Chang, C., Lee Luo, C., Gao, Y.
In crystallo observation of three metal ion promoted DNA polymerase misincorporation. 
Nat Commun, 13, pp. 2346 - 2346, 2022.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 98.616   b = 98.616   c = 82.057 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1894 for 65891 reflections in the resolution range 37.88 to 1.55 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)