NDB ID: 8E85    PDB ID: 8E85     NAKB: 8E85 

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Title:

HUMAN DNA POLYMERASE ETA-DNA-RG-ENDED PRIMER-DGMPNPP TERNARY MISMATCH COMPLEX WITH MN2+

Molecular Description:

Deposited:

2022-08-25

Released:

2023-02-01

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Chang, C., Lee Luo, C., Eleraky, S., Lin, A., Zhou, G., Gao, Y.
Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. 
J.Biol.Chem., 299, pp. 102938 - 102938, 2023.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 98.199   b = 98.199   c = 81.798 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.205 for 46567 reflections in the resolution range 32.14 to 1.72 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)

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Biological Assembly coordinates (pdb format) 1

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

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