NDB ID: 8E88    PDB ID: 8E88     NAKB: 8E88 

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Title:

HUMAN DNA POLYMERASE ETA-DNA-RU-ENDED PRIMER-DGMPNPP TERNARY MISMATCH COMPLEX WITH MG2+

Molecular Description:

Deposited:

2022-08-25

Released:

2023-02-01

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Chang, C., Lee Luo, C., Eleraky, S., Lin, A., Zhou, G., Gao, Y.
Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. 
J.Biol.Chem., 299, pp. 102938 - 102938, 2023.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 98.347   b = 98.347   c = 81.171 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1964 for 17462 reflections in the resolution range 42.59 to 2.4 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)

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Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

Asymmetric Unit coordinates (cif format, Unix compressed(.gz))

Biological Assembly coordinates (pdb format) 1

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

XML | Complete with coordinates (xml format, GNU compressed(.gz))

XML | Coordinates only (xml format, GNU compressed(.gz))

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